Preheat the oven to 350°F (175°C).
In a skillet over medium heat, combine the cream, chopped chipotle peppers, garlic powder, onion powder, salt, and pepper. Cook for 5–7 minutes while stirring until smooth and slightly thickened.
Heat a large skillet over medium-high heat. Add the ground beef and cook for 7–10 minutes until browned and fully cooked. Drain excess fat if needed.
Warm the tortillas for about 20 seconds to make them easier to roll.
Divide the cooked beef evenly among the tortillas. Roll tightly and place seam-side down in a lightly greased baking dish.
Pour the creamy chipotle sauce evenly over the Smothered Ground Beef Burritos.
Sprinkle shredded cheddar cheese generously over the top.
Bake for 20–25 minutes until the cheese is melted, bubbly, and lightly golden.
Serve immediately with your favorite toppings like cilantro, diced tomatoes, sour cream, or sliced avocado.