In a large bowl, combine the ground turkey, breadcrumbs, egg, garlic powder, onion powder, smoked paprika, salt, and pepper until evenly mixed.
Preheat a grill or grill pan over medium heat and lightly oil the grates.
Divide the mixture into four equal patties and make a shallow indentation in the center of each.
Grill the Grilled Turkey Burgers with Spicy Jalapeño Slaw patties for 5–7 minutes per side, or until the internal temperature reaches 165°F (75°C).
Meanwhile, combine the cabbage, carrots, jalapeño, mayonnaise, apple cider vinegar, honey, and cilantro in a large bowl. Toss until well coated.
Toast the whole wheat buns on the grill for 1–2 minutes until lightly crisp.
Assemble the burgers by placing each turkey patty on the bottom bun, topping generously with the spicy jalapeño slaw, and adding the top bun. Serve immediately.